Cialis® 20 mg film-coated tablets by lilly

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Cialis® 20 mg film-coated tablets by lilly

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Tadalafil
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GENERIC NAME: tadalafil
BRAND NAME: Cialis
Manufacturer:
Delivery: 1tablets 20mg






Tadalafil is an oral drug that is used for treating impotence (the inability to attain or
maintain a penile erection) and benign prostatic hyperplasia (BPH). It is in a class of
drugs called phosphodiesterase-5(PDE5) inhibitors that also includes sildenafil (Viagra)
and vardenafil (Levitra). Erection of the penis is caused by the filling of the penis with
blood. Filling occurs because the blood vessels that bring blood to the penis increase in
size and deliver more blood to the penis, and, at the same time, the blood vessels that take
blood away from the penis decrease in size and remove less blood from the penis. Sexual
stimulation that leads to an erection causes the production and release of nitric oxide in
the penis. The nitric oxide causes an enzyme, guanylate cyclase, to produce cyclic guanosine
monophosphate (cGMP). It is cGMP that is primarily responsible for increasing and decreasing the
size of blood vessels carrying blood to and from the penis, respectively, and causing an erection.
When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to
their normal size, blood leaves the penis, and the erection ends. Tadalafil prevents
phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. The persistence of cGMP
leads to a more prolonged engorgement of the penis with blood.